Gx Inbeneo

The pressurised cartridge-based design of the Gx Inbeneo autoinjector platform enables self-administration of drugs of varying viscosity in large volumes. It minimises protein aggregation, shortens injection time, and enables clear progress monitoring for patients.   The Gx Inbeneo autoinjector platform concept offers pharmaceutical companies a robust solution for patients to self-administer viscous biologic drugs at home. The unique pre-pressurised design incorporates a pre-filled glass cartridge, which retains the spring force, enabling the use of stronger springs to inject up to 3mL of a highly viscose drug. As there is no need for a spring locking mechanism, there is no associated risk of failure. Unlike autoinjectors based on pre-filled syringes, the needle in the Gx Inbeneo is separated from the primary packaging until use, which eliminates the possibility of needle clogging during storage. The needle has a double-ended design with a thicker end to pierce the cartridge septum and a thinner end to piece the patient’s skin. This mitigates patient discomfort caused by a thicker needle while also enabling higher viscosities to be delivered in less time. The modular design allows independent selection of the needle, spring, and ISO cartridges of 1.5 mL or 3 mL, optimising injection time and facilitating quick adaptation to different drugs. A safety shield conceals the needle before and after use, preventing needle stick injuries and reducing patient anxiety. Patients simply press the device against their skin for smooth drug administration. The transparent top casing supplements the standard central window to enable easier injection progress monitoring and an audible click provides additional confirmation of injection completion. The pre-pressurised design also minimises gas bubbles, which reduces the risk of protein aggregation in sensitive biologics. Incorporating cartridges with baked-on siliconisation further mitigates this risk. Red Dot Award: Design Concept | Ready For Market | Medical Devices and Technology